ABSORPTION OF INJECTED TAURINE-S35 BY RAT ORGANS
نویسندگان
چکیده
منابع مشابه
Further studies of the metabolism of taurine-S35 by the rat.
In a recent study (1) of the metabolism of taurine-S35 and taurocholate-S35 in the rat, a significant tissue retention of labeled sulfur. was observed 24 hours after the administration of taurine-S36. This tissue retention was increased and the urinary excretion decreased by preparatory feeding of a diet low in organic sulfur. Machlin et al. (2) have observed that 65 per cent of injected sulfat...
متن کاملFurther Studies of the Metabolism of Taurine-s35 by the Rat*
In a recent study (1) of the metabolism of taurine-S35 and taurocholate-S35 in the rat, a significant tissue retention of labeled sulfur. was observed 24 hours after the administration of taurine-S36. This tissue retention was increased and the urinary excretion decreased by preparatory feeding of a diet low in organic sulfur. Machlin et al. (2) have observed that 65 per cent of injected sulfat...
متن کاملIn vivo metabolism of 9-methyl-6-mercaptopurine-S35 and 9-ethyl-6-mercaptopurine-S35 by the rat.
intraperitoneally to rats. The catabolic products of each of these compounds in the 24-hour urine after injection in these rats were determined. 6-MP-S36 was excreted primarily as thiouric acid. 9-Methyl and 9-ethyl-6-MP-S35 were primarily excreted unaltered, and no evidence of dealkylation was obtained. The import of these findings on the possible mechanism of action of 6-MP against neoplastic...
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INTRODUCTION In 1937, Holmgren and Wilander (10) main tained that mast cells in connective tissue contain a polysulfuric acid ester giving a heparin effect and that it is their function to secrete the anticoagula tive substance into the blood. This contention is supported by the finding that tissue which is rich in mast cells—e.g., the hepatic capsule of the cow —has more pronounced anticoa...
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Taurine, a sulphur amino acid found endogenously in human and in several others. It is significantly in higher concentration in mammals and has a number of physiological and pharmacological actions and also used in the therapy of important organ dysfunctions. It is essential for cat and conditional for humans. A patient on parenteral nutrition (PN) may develop taurine deficiency which may hampe...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64886-0